Ectodysplasin A in Biological Fluids and Diagnosis of Ectodermal Dysplasia
نویسندگان
چکیده
منابع مشابه
Diagnosis and treatment in anhidrotic ectodermal dysplasia with immunodeficiency.
Anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) is characterized according to its various manifestations, which include ectodermal dysplasia, vascular anomalies, osteopetrosis, and diverse immunological abnormalities such as susceptibility to pathogens, impaired antibody responses to polysaccharides, hypogammaglobulinemia, hyper-IgM syndrome, impaired natural killer cell cytotoxi...
متن کاملMutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia.
X-linked hypohidrotic ectodermal dysplasia (XLHED) is a heritable disorder of the ED-1 gene disrupting the morphogenesis of ectodermal structures. The ED-1 gene product, ectodysplasin-A (EDA), is a tumor necrosis factor (TNF) family member and is synthesized as a membrane-anchored precursor protein with the TNF core motif located in the C-terminal domain. The stalk region of EDA contains the se...
متن کاملComplications of Implant Rehabilitation in Ectodermal Dysplasia Patients: A Review Study
Background and Aim: Ectodermal dysplasia (ED) is a hereditary disease that affects ectodermal tissues. Its oral manifestations include hypodontia or oligodontia, which cause the reduction of the height and width of the alveolar ridge. Considering numerous difficulties that these patients encounter with regard to facial appearance, talking, and chewing, their rehabilitation has a major influence...
متن کاملEctodermal dysplasia and immunodeficiency.
EDITOR,-Immunodeficiency has been previously described in patients with ectodermal dysplasial; surprisingly it was not mentioned at all in the recent review article on ectodermal dysplasia in this journal.2 Immunodeficiency is not a constant feature in all patients with ectodermal dysplasia, it is often transient and variable and no consistent T or B cell abnormality has been found.' The exact ...
متن کاملPathogenesis of ectodermal dysplasia
Ectodermal dysplasias (ED) are characterized by impaired development of organs forming from the embryonic surface ectoderm. Thus, in ED organs like teeth, hair, nails and exocrine glands are hypoplastic or totally missing. The pathogenesis of the defects is starting to be understood thanks to the identification of the responsible gene mutations, and to the advances in developmental biology. Rap...
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ژورنال
عنوان ژورنال: Journal of Dental Research
سال: 2016
ISSN: 0022-0345,1544-0591
DOI: 10.1177/0022034516673562